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dietary
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98% ultra-pure trans-resveratrol
defend your cells
dietary
supplements
98% ultra-pure trans-resveratrol
defend your cells
Cardiovascular & Healthy Aging
The most-studied antioxidant compound in the world — and the source researchers actually use.
Resveratrol Plus® pairs 98% ultra-pure trans-resveratrol with four supporting botanicals chosen for one job: helping your cells and cardiovascular system hold their ground against the oxidative stress of aging.
You already know antioxidants matter. What most people never get told is which form of resveratrol the research is actually built on — and why the cheap grape-skin versions on the shelf aren't it. Start here.
Cardiovascular & Healthy Aging
The most-studied antioxidant compound in the world — and the source researchers actually use.
Resveratrol Plus® pairs 98% ultra-pure trans-resveratrol with four supporting botanicals chosen for one job: helping your cells and cardiovascular system hold their ground against the oxidative stress of aging.
You already know antioxidants matter. What most people never get told is which form of resveratrol the research is actually built on — and why the cheap grape-skin versions on the shelf aren't it. Start here.
defend your cells from the inside out
The mechanism
Your cells are aging faster than they should.
Here's the quiet reason.
Every day, your body is exposed to free radicals — unstable molecules produced by normal metabolism, sun, pollution, and stress. When they outpace your antioxidant defenses, the result is oxidative stress: a slow, cumulative strain on your cells and the tissue lining your blood vessels. Researchers consider it one of the central drivers of cardiovascular aging and the gradual loss of vitality that can come with the decades.1
You can't stop oxidation — it's the cost of being alive. But you can give your body more of the compounds that help neutralize it. That's the entire idea behind this formula: not one antioxidant, but a small, deliberate stack of them, each studied for a different part of the same problem
Below are the five that matter most for your heart and your healthy-aging years — what each one is, what the research says it does, and why it's in the bottle.
The five compounds
Five ingredients. One job: defend
the cardiovascular system.
ingredient 1
Trans-Resveratrol
98% pure · from Japanese Knotweed · 600 mg
This is the compound everything else is built around — and the form matters more than most labels admit. Resveratrol exists in two forms, cis and trans; trans-resveratrol is the bioactive, well-absorbed form that nearly all the human research is conducted on. Cheaper supplements often lean on low-grade grape-skin extract with little of it. This formula uses 98% ultra-pure trans-resveratrol from Japanese knotweed — the same research-grade source scientists actually study.
What the research points to: resveratrol is studied for activating sirtuins (SIRT1) — a family of proteins involved in cellular repair and the regulation of aging. As an antioxidant, it also helps counter the oxidative stress that strains cardiovascular tissue, and a meta-analysis of randomized controlled trials found resveratrol reduced systolic blood pressure at higher doses.
Why it matters for you: it works at the level where cardiovascular aging actually begins — the cell.
"You've heard of antioxidants. This is the one — and the form — researchers actually use."
ingredient 2
Grape Seed Extract
Standardized to 95% proanthocyanidins · 250 mg
If resveratrol works inside the cell, grape seed works on the plumbing. Its active compounds, proanthocyanidins, are studied for supporting the endothelium — the delicate lining of your blood vessels — partly by helping the body produce nitric oxide, the molecule that lets vessels relax and blood flow freely.
What the research points to: a meta-analysis of nine randomized controlled trials found grape seed extract significantly lowered systolic blood pressure.
Why it matters for you: healthy circulation is how every other nutrient — and every breath of oxygen — actually reaches the tissue that needs it.
"Resveratrol works inside the cell. Grape seed works on the vessels that feed it."
ingredient 3
French Maritime Pine Bark
Pinus pinaster · 100 mg
This is the ingredient most resveratrol products leave out — and the reason this one reads as a serious cardiovascular formula. Extracts of French maritime pine bark are among the most-studied botanicals for endothelial function: in a double-blind human study, supplementation improved endothelium-dependent vasodilation — the blood vessels' ability to relax and widen — by enhancing nitric oxide availability.
What the research points to: vessel flexibility is one of the first things to stiffen with age. This is a direct, well-researched lever on it.
"Most resveratrol products stop at one ingredient. Here's the one that puts circulation first."
ingredient 4
Quercetin
From Japanese Pagoda Tree · 200 mg
Quercetin is the most abundant flavonol in the human diet, and it's here to do two things resveratrol can't do alone: broaden the antioxidant coverage, and complement the cardiovascular picture. It's well studied as an antioxidant in cardiovascular research, and a meta-analysis of randomized controlled trials found quercetin supplementation produced significant reductions in blood pressure.
What the research points to: antioxidants work as a team, not as soloists. Quercetin widens the net so fewer free radicals slip through.
"Antioxidants don't work alone. Quercetin is the teammate resveratrol was waiting for."
ingredient 5
Cinnamon Bark Extract
Cinnamomum cassia · 200 mg
The fifth compound addresses the metabolic side of cardiovascular wellness. Cinnamon bark is traditionally valued for circulation and is studied today for metabolic balance: an umbrella review of randomized-controlled-trial meta-analyses found cinnamon supplementation was associated with improvements in fasting blood glucose and lipid profiles.
What the research points to: blood sugar and lipids are quietly tied to long-term heart and vessel health — this rounds out the formula from the metabolic angle.
"Cardiovascular wellness isn't only about the heart. It's about what's moving through it."
The five compounds
Five ingredients. One job: defend the cardiovascular system.
ingredient 1
Trans-Resveratrol
98% pure · from Japanese Knotweed · 600 mg
This is the compound everything else is built around — and the form matters more than most labels admit. Resveratrol exists in two forms, cis and trans; trans-resveratrol is the bioactive, well-absorbed form that nearly all the human research is conducted on. Cheaper supplements often lean on low-grade grape-skin extract with little of it. This formula uses 98% ultra-pure trans-resveratrol from Japanese knotweed — the same research-grade source scientists actually study.
What the research points to: resveratrol is studied for activating sirtuins (SIRT1) — a family of proteins involved in cellular repair and the regulation of aging. As an antioxidant, it also helps counter the oxidative stress that strains cardiovascular tissue, and a meta-analysis of randomized controlled trials found resveratrol reduced systolic blood pressure at higher doses.
Why it matters for you: it works at the level where cardiovascular aging actually begins — the cell.
"You've heard of antioxidants. This is the one — and the form — researchers actually use."
ingredient 2
Grape Seed Extract
Standardized to 95% proanthocyanidins · 250 mg
If resveratrol works inside the cell, grape seed works on the plumbing. Its active compounds, proanthocyanidins, are studied for supporting the endothelium — the delicate lining of your blood vessels — partly by helping the body produce nitric oxide, the molecule that lets vessels relax and blood flow freely.
What the research points to: a meta-analysis of nine randomized controlled trials found grape seed extract significantly lowered systolic blood pressure.
Why it matters for you: healthy circulation is how every other nutrient — and every breath of oxygen — actually reaches the tissue that needs it.
"Resveratrol works inside the cell. Grape seed works on the vessels that feed it."
ingredient 3
French Maritime Pine Bark
Pinus pinaster · 100 mg
This is the ingredient most resveratrol products leave out — and the reason this one reads as a serious cardiovascular formula. Extracts of French maritime pine bark are among the most-studied botanicals for endothelial function: in a double-blind human study, supplementation improved endothelium-dependent vasodilation — the blood vessels' ability to relax and widen — by enhancing nitric oxide availability.
What the research points to: vessel flexibility is one of the first things to stiffen with age. This is a direct, well-researched lever on it.
"Most resveratrol products stop at one ingredient. Here's the one that puts circulation first."
ingredient 4
Quercetin
From Japanese Pagoda Tree · 200 mg
Quercetin is the most abundant flavonol in the human diet, and it's here to do two things resveratrol can't do alone: broaden the antioxidant coverage, and complement the cardiovascular picture. It's well studied as an antioxidant in cardiovascular research, and a meta-analysis of randomized controlled trials found quercetin supplementation produced significant reductions in blood pressure.
What the research points to: antioxidants work as a team, not as soloists. Quercetin widens the net so fewer free radicals slip through.
"Antioxidants don't work alone. Quercetin is the teammate resveratrol was waiting for."
ingredient 5
Cinnamon Bark Extract
Cinnamomum cassia · 200 mg
The fifth compound addresses the metabolic side of cardiovascular wellness. Cinnamon bark is traditionally valued for circulation and is studied today for metabolic balance: an umbrella review of randomized-controlled-trial meta-analyses found cinnamon supplementation was associated with improvements in fasting blood glucose and lipid profiles.
What the research points to: blood sugar and lipids are quietly tied to long-term heart and vessel health — this rounds out the formula from the metabolic angle.
"Cardiovascular wellness isn't only about the heart. It's about what's moving through it."
Why one formula
Five bottles, or one formula with nine compounds.
You could chase all of this down separately. Research-grade trans-resveratrol from Japanese knotweed. Standardized grape seed. French maritime pine bark. Quercetin. Cinnamon. That's five different bottles, five different brands, five different purity standards — and no guarantee any of them are using the forms the research is actually based on.
And we didn't stop at five. The full formula carries nine targeted compounds in a single daily serving — 1,750 mg, in 90 vegetable capsules — formulated by a brand that has been doing exactly this for 35 years. Clean, non-GMO, vegan, lab-tested, and made in the USA.
9
targeted
compounds
1,750 mg
Per daily
serving
35
Years of formulation
One formula. One capsule routine. Built the way the
research says it should be.
defend your cells from the inside out
Why one formula
Five bottles, or one formula with nine compounds.
You could chase all of this down separately. Research-grade trans-resveratrol from Japanese knotweed. Standardized grape seed. French maritime pine bark. Quercetin. Cinnamon. That's five different bottles, five different brands, five different purity standards — and no guarantee any of them are using the forms the research is actually based on.
And we didn't stop at five. The full formula carries nine targeted compounds in a single daily serving — 1,750 mg, in 90 vegetable capsules — formulated by a brand that has been doing exactly this for 35 years. Clean, non-GMO, vegan, lab-tested, and made in the USA.
9
targeted compounds
1,750 mg
Per daily serving
35
Years of formulation
One formula. One capsule routine. Built the way the
research says it should be.
defend your cells from the inside out
Begin the routine
Give your cells the form of
resveratrol the research is built on.
98% ultra-pure trans-resveratrol, four supporting botanicals, nine compounds, one daily serving — backed by a 60-day money-back guarantee.
vegan capsules
•
lab tested
•
doctor formulated
•
98% trans-resveratrol
•
made in the usa
vegan capsules
•
lab tested
•
doctor formulated
•
98% trans-resveratrol
•
made in the usa
•
“We designed this blend to be more complete than a typical resveratrol product, using carefully selected plant compounds that complement one another for antioxidant, circulation, and vascular health support.”
Denys Tsveiuk
Medical Doctor, Certified Nutritional Therapist & Chief Science Officer to SupplementMD app.
references
Harrison DG, Gongora MC. Oxidative stress and hypertension. Med Clin North Am. 2009;93(3):621–635.
Linus Pauling Institute, Micronutrient Information Center. Resveratrol. Oregon State University.
Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem. 2005;280(17):17187–17195.
Liu Y, Ma W, Zhang P, He S, Huang D. Effect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials. Clin Nutr. 2015;34(1):27–34.
Feringa HHH, Laskey DA, Dickson JE, Coleman CI. The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials. J Am Diet Assoc. 2011;111(8):1173–1181.
Nishioka K, et al. Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans. Hypertens Res. 2007;30(9):775–780.
Serban MC, et al. Effects of quercetin on blood pressure: a systematic review and meta-analysis of randomized controlled trials. J Am Heart Assoc. 2016;5(7):e002713.
Cinnamon supplementation and metabolic outcomes: an umbrella review of meta-analyses of randomized controlled trials. 2025.
IMPORTANT
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Cited studies refer to the individual compounds and do not represent claims about this finished product.
2026 © Nora Ross, Inc.